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The Cafe is a renowned LGBTQ+ nightclub and bar located in the Castro District of San Francisco, United States. Established in 1995, The Cafe quickly became an integral part of the city's vibrant queer nightlife scene. Known for its welcoming and inclusive environment, it has long served as a safe space for members of the LGBTQ+ community and their allies.

The venue gained popularity through its themed dance nights, drag performances, and high-energy DJ events, earning a reputation as both a nightspot and a community hub. Over the years, The Cafe has undergone significant structural changes, most notably a major renovation and expansion completed in 2013 that transformed the interior into a sleek, modern multi-level space featuring a spacious dance floor, state-of-the-art lighting, and a balcony overlooking the action below. Its location at 2369 Market Street has remained constant, anchoring it firmly in the heart of the Castro while other venues have come and gone, reinforcing its significance in the neighborhood’s ongoing LGBTQ+ history.

The Cafe gained further recognition for its role in hosting social and charitable events, cementing its place as a cornerstone of both celebration and advocacy within the local community. Its visibility and enduring popularity have made it a cultural landmark, frequently referenced in media and regarded as a must-visit nightspot for visitors to San Francisco. Notable artists who have performed at The Cafe include international DJ names such as DJ Hector Fonseca and DJ Wayne G, as well as celebrated local talents like DJ MC2 and DJ Kidd Sysko.

The venue has also hosted drag superstars such as RuPaul’s Drag Race alumni Alyssa Edwards, Trixie Mattel, and Shangela, alongside San Francisco drag legends like Juanita MORE! and Heklina.