Panama is a renowned nightclub and event venue located in Amsterdam, Netherlands. Established in 2001, Panama has become one of the city’s premier nightlife destinations, celebrated for its cutting-edge sound system, immersive lighting, and industrial-chic atmosphere. The venue occupies a former harbor warehouse at Oostelijke Handelskade 4, close to the IJ River, lending it a distinctive, spacious feel that reflects Amsterdam’s maritime history.

Over the years, Panama has carved out a significant place in the cultural landscape of the city, hosting a diverse range of events including club nights, live concerts, theater performances, and private gatherings. Its reputation is built on a commitment to musical diversity and quality entertainment, attracting both local residents and international visitors. The venue's flexible space, featuring a main hall and upper gallery, supports a variety of configurations, making it a hotspot for everything from electronic music parties to corporate events.

Since its inception, Panama has maintained its original location, though it has undergone several renovations to update its facilities, enhance acoustic performance, and meet evolving audience expectations. Its enduring popularity is a testament to its adaptability, innovative event programming, and contributions to Amsterdam’s thriving nightlife and cultural scenes. Notable artists who have graced Panama’s stage include international acts like David Guetta, Armin van Buuren, Paul van Dyk, Martin Garrix, Carl Cox, Roger Sanchez, and DJ Chuckie, as well as Dutch favorites such as Fedde Le Grand, Laidback Luke, Sunnery James & Ryan Marciano, and Hardwell.

These performances have solidified Panama's status as a key venue for both established and emerging talent in the electronic music world.