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ISOamsterdam, located at Isolatorweg 17 in the northwest industrial zone of Amsterdam, is a unique nightclub and creative hub that has played a significant role in the city’s underground electronic music scene. Occupying a repurposed industrial warehouse, ISOamsterdam has its roots in the area's rich history as a hub for manufacturing and logistics, which lends the venue its distinct raw and spacious aesthetic. ISOamsterdam began as a workspace for artists, musicians, and technologists, gradually transforming into a multidisciplinary space that blends nightlife, art, and innovation.

The venue is praised for its commitment to inclusivity, sustainability, and experimentation, often serving as a launchpad for cutting-edge electronic music acts and avant-garde artistic expressions. While it remains primarily in its original location at Isolatorweg 17, the venue has evolved over time with expansions and adaptive renovations, enhancing acoustics and visual installations while maintaining its industrial charm. ISOamsterdam is celebrated for fostering collaborations between local creatives and internationally renowned artists, gaining a reputation as a cultural incubator that pushes the boundaries of nightlife and creative production in Amsterdam.

Notable artists who have performed at ISOamsterdam include international figures such as DJ Stingray 313, Objekt, Helena Hauff, and Interstellar Funk, alongside local heroes like Oceanic, Mary Lake, Suze Ijó, and Job Sifre.