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There appears to be some confusion regarding "Descanso Gardens" as a nightclub in the United States. In reality, Descanso Gardens is a renowned botanical garden located in La Cañada Flintridge, California, on the northern edge of Los Angeles. Established in 1953, the gardens are celebrated for their impressive collections of camellias, roses, and native plants, and they occupy land that once served as the estate of newspaper magnate E.

Manchester Boddy. Over the decades, Descanso Gardens has gained cultural significance as a peaceful retreat and a site for environmental education, family outings, and special events such as the popular Enchanted: Forest of Light installation and public concerts. However, the venue has never functioned as a nightclub, nor has it hosted recurring nightlife entertainment typical of such establishments.

Instead, the structural changes to Descanso Gardens over time have included expansions of walking trails, new themed gardens, and amenities for visitors, all aimed at enhancing its role as a public green space. Despite this, Descanso Gardens has occasionally played host to musical performances and cultural happenings, but these are usually part of seasonal festivals or garden parties rather than regular club nights. There is no history or record of internationally or locally notable nightclub artists performing at Descanso Gardens in the context of a nightclub experience, as it remains a botanical and art-focused venue rather than a nightlife destination.

For this reason, there is no list of notable artists, international or local, who have performed at Descanso Gardens in the context of nightclub events.