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Club NYX is a renowned nightclub located in Amsterdam, Netherlands, distinguished for its vibrant and inclusive atmosphere that embraces diversity across all spectrums—sexual, cultural, and musical. Opened in 2011 on Reguliersdwarsstraat, one of the city’s most celebrated nightlife streets, Club NYX quickly became an iconic destination within the LGBTQIA+ community, while at the same time drawing a broad, open-minded crowd. Its name playfully references the ancient Greek goddess of the night, and this mythical veneer is reflected in the electric, uninhibited energy that pulses through the venue every weekend.

Club NYX set itself apart from more traditional nightclubs by adopting a multi-floor layout, often operating three stories under one roof, each with distinct musical identities and design aesthetics—from cutting-edge electronic sounds to pop, hip-hop, and disco. Over the years, the club's “anything goes” philosophy has fostered an environment famous for its wild parties, themed nights, and creative variety. In its decade-plus of operation, NYX has cemented its status both as a safe space for young people discovering their identities and as a fearless party powerhouse for locals and international tourists eager to experience Amsterdam’s famously liberal nightlife.

The club occupies a historic building that has maintained its original facade, though the interior has seen periodic refurbishments—often with playful, boundary-pushing decor and multiple dancefloors—as the club owners responded to ever-evolving trends and crowds. While NYX has always operated at its original Reguliersdwarsstraat address, it has undergone several renovations to increase capacity and improve sound systems, maintaining its standing at the cutting edge of the city’s club scene. Today, Club NYX continues to redefine nightlife in Amsterdam, standing out for its progressive ethics, genre-bending music policies, and boundary-smashing events that have earned it a devoted following and significant cultural cachet within the Netherlands and beyond.

Notable artists who have graced the decks and stages at Club NYX include international acts such as Jodie Harsh, Honey Dijon, The Blessed Madonna, and Violet Chachki, alongside celebrated local talents like Shady Lady, Jeff Solo, Viccc, David Vunk, Disko Disko, and Tommie Sunshine. These artists represent a broad array of musical backgrounds, echoing the club’s commitment to diversity and nonconformity in its musical programming.