Apotheke is a prominent cocktail lounge and speakeasy located in New York City, well-regarded for its innovative approach to mixology and immersive ambiance. Opened in 2008 in the heart of Manhattan’s Chinatown, the venue’s name—which means "pharmacy" in German—eloquently mirrors its concept: the bar’s décor echoes the look of an old-world apothecary, with bartenders dressed in lab coats mixing cocktails drawn from an extensive "prescription" menu. Apotheke swiftly garnered a devoted following for its theatrical presentation, commitment to high-quality ingredients, and inventive concoctions inspired by herbal remedies and global flavors.

Its covert entrance, modeled after the speakeasies of the Prohibition era, added an air of exclusivity and intrigue, cementing its reputation as one of New York’s most atmospheric and experimental drinking establishments. Over time, Apotheke’s influence helped shape the cocktail culture of the city, becoming an emblem of the early 21st-century speakeasy revival and nurturing a generation of mixologists who have gone on to lead notable bars around the world. In 2022, the original Chinatown location was joined by a second outpost in Los Angeles, further expanding the venue’s reach and updating its concept with a larger, more modern space while maintaining the signature artistic flair and apothecary theme.

Throughout both locations, the focus has remained on creative mixology and curated musical experiences, enhancing the overall allure of the brand. While Apotheke is primarily celebrated for its cocktails rather than live musical sets, it has nonetheless played host to a variety of performances, themed nights, and collaborations with musicians and DJs, attracting a sophisticated clientele and contributing to New York’s rich nightlife tapestry. Notable artists who have performed or made appearances at Apotheke include internationally recognized DJs such as Questlove, DJ Logic, and Natasha Diggs, as well as acclaimed jazz artists like Roy Hargrove and local talents including DJ Spinna and DJ Center.

The venue has also featured curated music nights by renowned collectives and frequent collaborations with influential figures from New York’s creative scene, such as musicians from the Brooklyn Raga Massive and various underground performers who blend world music, jazz, and electronic genres.